Neurodevelopmental Toxicity of Aluminum Compounds

How much do we know about aluminum? It has been used in various applications for the past 90 years, which would lead one to assume that it’s a safe and effective compound. However, this assumption has very little research backing its ‘beneficial’ use and quite a significant body of research describing its toxic effects on the brain and immune system. Parents, doctors and scientists are asking why it continues to be formulated in things like vaccines, infant formula and other ingestible sources?

Two researchers from Children’s Medical Safety Research Institute took a look at various aluminum sources and their adverse effects in an animal model and in humans.  The purpose of their study was to evaluate the effects of pediatric vaccine relevant quantities of aluminum adjuvants on cognitive, motor and behavioral function, as well as to evaluate biological and genetic changes that take place after injected exposures to aluminum adjuvants. By comparing the outcomes of the exposed mice to a control group that received a true inert saline placebo, the effects of aluminum in the vaccine schedule could be isolated and quantified. This study has provided significant evidence that aluminum is more harmful than the public has perceived it to be, and it is clear that aluminum is a dangerous neurotoxin.

In the research, Dr. Christopher Shaw and Dr. Lucia Tomljenovic studied a number of aluminum sources/compounds and how they affected the individual or animal that was exposed. In the chart of data they compiled, they noted the amount of aluminum found in standard infant feeding solution where premature infants were exposed to about ~20 μg/kg a day. The aluminum-formulated solution resulted in a reduced developmental attainment at the post-term age of 18 months compared to infants who were fed with aluminum-depleted solutions. This significant neurodevelopmental change is one of the many data sets found in the chart that compares the effects of non-aluminum compounds to aluminum-sourced compounds.

To support their findings, human exposure data included symptom changes for patients suffering from renal/kidney failure. These patients were exposed to to aluminum-tainted dialysis fluid while being treated for their condition. However, they discovered that the dialysis fluid actually made their symptoms much worse. Some of the noted symptoms after the aluminum-tainted dialysis fluid treatment began included:

  • Impaired concentration
  • Behavior changes
  • Epileptic seizures
  • Coma
  • Memory loss
  • Speech problems
  • And more

These symptoms were not present before the dialysis began and interestingly enough, the patients who suffered from these side effects took a turn for the better when aluminum was removed from the dialysis fluid. This key example is strong evidence that the aluminum-tainted dialysis fluid was the culprit behind the symptoms, yet the use of aluminum continues. Additionally, the researchers point out that aluminum has a great potential to act as a toxic co-factor in the onset of many neurodegenerative diseases like autism, Alzheimer’s, Parkinson’s and other conditions. With the large amount of scientific research outlining the adverse effects of aluminum, the compound should be given more scrutiny and oversight as its presence in medicines, vaccines and consumer products has increased significantly over the last three decades. As aluminum’s increased use has coincided with an increased rate of chronic illness and disability, and there is ample scientific evidence linking aluminum to immune and neurotoxicity, reconsidering its approval in products that humans use or consume could reduce the frequency of chronic illness cases.

Three Women Suffer from Primary Ovarian Failure Following HPV Vaccination

Funded CMSRI researchers conducted a study, after three women developed secondary amenorrhea and primary ovarian failure following HPV vaccinations. Lucija Tomljenovic and Yehuda Shoenfeld found links to the development of their conditions and the adjuvants found in HPV vaccinations.

The researchers partnered with Serena Colafrancesco and Carlo Perricone to fully investigate the issue. All three women suffered from secondary amenorrhea, which is the absence of a menstrual cycle.

Their problem was not resolved using hormone replacement therapies. The researchers found auto-immune antibodies in two of the patients, anti-ovarian and anti-thyroid respectively, suggesting that the HPV vaccine triggered an autoimmune response. However, all three patients experienced common post-vaccination symptoms including:

  • Nausea
  • Headache
  • Sleep disturbances
  • Arthralgia
  • A range of cognitive and psychiatric disturbances

The researchers concluded that evidence of adjuvants in the HPV vaccine could trigger a life-disabling autoimmune condition, as they saw with the amenorrhea.

In recent news, a new syndrome, called autoimmune/inflammatory syndrome induced by adjuvants (ASIA), or Shoenfeld’s syndrome, has been making its way into the medical field.

ASIA involves immune-mediated conditions that appear following a chronic stimulation of the immune system, by agents with adjuvant characteristics.

The post-vaccination autoimmune responses are a major concern regarding ASIA. HPV vaccines and others are known for their use of aluminum adjuvants, which are neurotoxins. These adjuvants are creating correlations between adverse reactions, as these cases suggest. Two of the patients who were studied were sisters who both developed primary ovarian failure. The sisters, 13 years old and 14 years old, received three HPV vaccinations with worsening side effects, including irregular periods, thereafter, resulting in a total absence of their menstrual cycles.

The third woman began the administration of the HPV vaccine at the age of 21 and developed irregular menstrual cycles. The patient underwent therapy, but by the age of 23, she suffered from amenorrhea and Medroxy-progesterone. Estradiol therapy was attempted but it did not improve her clinical condition.

Tomljenovic and Shoenfeld ruled out all other possible causes for the three patients diagnosed with primary ovarian failure (POF). They concluded that the HPV vaccination was the root of the adverse reactions because the patients were all clinically healthy before they were vaccinated.

Among the startling statistics regarding POF, it only affects one percent of women under 40 years old and 0.01 percent of women under the age of 20. It is an important cause of infertility and psychological stress. The results can have significant consequences for these women’s future health and their prospects of motherhood. The origins of POF have been widely debated and the evidence found in this case strongly supports its association with toxic adjuvants entering the body and negatively manipulating autoimmune responses.

Drastic Increase of Autism Reported

Autism spectrum disorder (ASD) has a prevalence of 1 in 68 children – a 30% increase since 2012 according to the Center for Disease Control and Prevention (CDC). ASD was once a rare disorder but is occurring more frequently than before, as more cases are being diagnosed each year. The reason for this increase may be linked to certain ingredients found in vaccines, specifically aluminum formulated vaccines. Dr. Stephanie Seneff, a funded CMSRI researcher, has reviewed empirical data that confirms autism symptoms related to aluminum and acetaminophen exposure.

Autism and ASD can be defined as a condition characterized by impaired cognitive and social skills along with compromised immune function. The fact that ASD rates have rapidly increased over the last two decades suggests that there are environmental components that lead to its prevalence. The root cause of ASD is still unknown; however, current research is suggesting that the use of vaccines are playing a role in its development. In her review titled Empirical Data Confirm Autism Symptoms Related to

Aluminum and Acetaminophen Exposure, Dr. Seneff points out the word frequency patters in the CDCs Vaccine Adverse Events Reporting System (VAERS) database.

The VAERS is a database executed by the U.S. government that allows doctors and patients to report any adverse reactions noted in association with vaccines. After conducting a search of the words “autism” and “autistic,” Dr. Seneff plotted the word frequencies based on year and could visually graph spikes in adverse reactions with vaccines and the aforementioned keyword.


“The incidence of autism-related adverse events in the VAERS database continued to rise over the time period after the amount of thimerosal in the vaccines had been sharply reduced. We hypothesize that this unanticipated consequence is due to simultaneous increases in the aluminum content, attributed to an increased number of required vaccines, intentional addition of aluminum to achieve an adjuvant effect, as well as the likely further accumulation of aluminum as a consequence of leaching, given the new practice of storage in individual glass vials with rubber stoppers. We identified several severe adverse reactions that were much more prevalent in reports from the second decade of the data, and showed that these same symptoms were also much more prevalent for reports involving aluminum-containing vaccines compared to reports on vaccines without aluminum, over the entire data set. These symptoms include seizure, cyanosis, gaze palsy, depression, fatigue, insomnia, and death.”

With the above database available from the CDC, researchers can find specific trends relating aluminum to autism by the noted adverse reactions. As autism continues to be a prevalent disorder with more cases emerging everyday, suggesting the use of aluminum in vaccines could be a part of its cause is plausible. It could be hypothesized that if aluminum is forgone in vaccines and other products, autism cases have the potential to decrease.

Who’s Guarding What?

May 2006, the Gardasil vaccine was approved for use in the United States in a bid to stop the spread of four strains of the human papillomavirus (HPV) which can lead to cervical cancer. Since then, media outlets have highly praised the vaccine and it has been marketed and promoted all over the world, whilst the vaccines adverse side effects have been pushed aside, leaving those with negative reactions to suffer.

Did you know that there are over 100 strains of the HPV virus, which is a sexually transmitted disease?  How can a vaccine be highly praised when 96% of the strains continue to pose a risk – is the vaccine worth it?

Longitudinal studies have not been completed in regards to this relatively ‘new’ vaccine and this may lead to major concerns and ramifications if it’s continued to be injected into women. For several decades, numerous case reports and studies documenting neurological and autoimmune adverse reactions following the use of various vaccinations have been conducted but not for the HPV vaccines.

Two researchers funded by the Children’s Medical Safety Research Institute, Christopher Shaw and Lucija Tomljenovic, found two young women who suffered from fatal cerebral vasculitis-type symptoms, following a vaccination with the HPV vaccine Gardasil. Cerebral vasculitis is a serious disease, typically resulting in deadly outcomes if it is left undiagnosed and untreated. In some cases vaccination may be the triggering factor of fatal autoimmune/neurological events.

Shaw and Tomljenovic discovered an interesting correlation that involved certain antibodies and antigens found in Gardasil. They discovered that these antibodies and antigens were stained in the brain tissue of two women. This link might have explained the death of these individuals because the autoimmune vasculitis may have potentially been triggered by the cross-reactive HPV-16L1 antibodies found in Gardasil.

The case study showed signs of the two women having antibodies and antigens adhered to their post-mortem brain tissue. Some of the Gardasil antibodies were binding to the wall of the cerebral blood vessels, causing the body to abnormally activate an immune response so as to attack the antibodies; however, the response triggered the immune attack towards self-tissue, resulting in a fatal outcome.

Shaw and Tomljenovic concluded that HPV vaccines containing HPV-16L1 antigens, pose an inherent risk for triggering potentially fatal autoimmune vasculopathies. The HPV vaccine Gardasil continues to be used on many young women around the world, even though its adverse effects are beginning to surface.

Could The Use Of Antiperspirants Be Linked To Breast Cancer?

Antiperspirants are used by millions, if not billions of people worldwide. They are generally used to combat body odour and prevent underarm perspiration. However, antiperspirants contain many chemicals, whether you chose to use the gel based application, the solid bar product or the widely used aerosol spray.

What many people are unaware of is the fact that some antiperspirants are aluminum-based and aluminum is a non-essential metal in the human body, since it is permeable to the skin and can easily be absorbed. This being the case, scientists have questioned whether or not there is a correlation between the constant use of aluminum-based antiperspirants and the growing number of women developing breast cancer..

Since ‘breast cancer is the most common malignancy found in women and the leading cause of death among women aged 35-54, there may be a relationship between breast cancer and aluminum. The daily application of antiperspirant could result in the presence of aluminium in underarm tissue and the surrounding areas but there has been almost no data or research on the topic until recently.

There are a few potential factors that can cause breast cancer, including genetics and environmental factors; however the root cause of the disease is still unknown.

Dr. Christopher Exley, a scientist funded by the Children’s Medical Safety Research Institute, has recently conducted a study focusing on 17 women with breast cancer from the UK. Upon studying the patient’s cancerous breast tissues, he discovered that an alarming number of the women had traces of aluminum within the tissues.

Each patient in the study underwent a mastectomy and biopsies were taken from four different regions of the breast, the outer (axilla and lateral) and the inner (middle and medial). Upon examination of the breast tissues, aluminum content was identified in each region but no significant differences were found in the concentrations of aluminum. However, there were clear trends within each of the individual’s breast tissue that indicated the distribution of aluminium, across the breast.

After collecting the data, a matched-pair analysis showed that the aluminum concentration was not evenly distributed and the aluminum found in the outer breast region was significantly higher than the inner breast region. This analysis may be linked to the daily underarm use of aluminum-based antiperspirants because a higher concentration of aluminium was discovered near the outer breast tissue.

In the study, Dr. Exley was able to confirm the presence of aluminum in the cancerous breast tissue and its possible regional distribution within the breast. “Higher content of aluminum in the outer breast tissue may be explained by this region’s closer proximity to the underarm, where the highest density of application of antiperspirant, could be assumed.”

As more studies indicate the adverse reactions to aluminum in the body, it may raise awareness to eventually end the usage of this non-essential metal.

With Ebola in the News, it’s Time to Talk Vaccine Research

The Ebola virus has been a hot topic of discussion in the news over the past couple of weeks but the virus has actually been around for quite some time. It first emerged in Africa during the mid-1970’s and is believed to be carried and transmitted by the fruit bat. Once contracted by a human, the incubation period can be anything from two days to three weeks. Symptoms include fevers, headaches, sore throats and muscle pain followed by a rash, vomiting, diarrhoea and a decreasing liver and kidney function.

Between 1976, when the Ebola virus first appeared and 2013, the World Health Organization had reported 1,716 cases. The 2014 outbreak in Africa saw numbers rise to a staggering 2,615, as the outbreak began to spread to other parts of the globe. The medical profession has found it increasingly difficult to cure the virus because as yet, there isn’t a sufficient solution that can be mass produced.

Currently, there are efforts to regress and cure Ebola and USA Today has reported that two American missionaries who contracted the virus, whilst working in West Africa, received an experimental treatment and have been released from hospital. Doctors treating the missionaries reported that their former patients are no longer contagious and do not pose a threat to others. However, the treatment that the two individuals received upon their stay in hospital is questionable.

The missionaries were administered with the experimental vaccine ZMapp, even though human testing was never completed and ZMapp was still being tested on animals. No human clinical trials have so far been conducted and the side effects of the vaccine are yet to be discovered because of the lack of research. This raises concerns because the treatment could potentially only act as a ‘band-aid’ to a serious threat. The World Health Organization has announced that the treatment was based upon the ‘particular circumstances’ surrounding the Ebola virus outbreak and mentioned that the efficacy and adverse effects of the vaccine are unknown

The drug manufacturer of ZMapp claims that there is no longer any more of the vaccine left and doctors have yet to see proof of whether ZMapp had been successful, even though the patients showed no signs of the Ebola virus in their bodies. Although the two Americans have been released from the hospital, it is said that the Ebola virus can have an incubation period of up to 21 days. In the event that more ZMapp is produced and sent for more clinical trials, the long-term side effects will remain unknown due to lack of research.

Our goal at CMSRI is to raise awareness of the toxins and adverse effects vaccines pose to the human body. This new, experimental vaccine should be placed under the same scrutiny because the long-term effects have yet to be discovered or studied.

Are You Getting All The Information From The Doctor?

When a patient visits a doctor, they will be informed of risks and side effects regarding medications and surgery. Consent from the patient is required in order to receive any type of treatment or medication; however, when it comes to vaccinations, doctors do not tell all – simply because they do not know all the risks associated with vaccines and are not required to tell patients.

In the United States, there are no governmental requirements for informed consent for vaccination. This raises a red flag in terms of information because a mass-marketed vaccination like the HPV vaccine has insufficient data and research on how it can affect the body – leaving many patients in the dark.

Funded researchers of Children’s Medical Safety Research Institute have drawn the line of this ethical dilemma through studies conducted by Lucija Tomljenovic and Christopher Shaw. HPV vaccinations are often promoted by the world’s leading medical authorities, saying the HPV vaccines are an important cervical cancer prevention tool, yet clinical trials show no evidence that HPV vaccination can protect against cervical cancer.

In other parts of the globe, patients receive more information than their American counterparts but this poses the question – do those doctors fully understand the risks? In the United Kingdom, guidelines pertaining to vaccination practices state that patients must be given adequate information on which to base their decision on whether to accept or refuse a vaccine. What’s alarming is the lack of sufficient scientific research.

As HPV vaccines are claimed to prevent cervical cancer – it still remains unproven. The death rate of cervical cancer stands at 1.7 out of 100,000 according to the World Health Organization. But, the rate of serious adverse reactions to the HPV vaccine stands at 4.3 out of 100,000. A serious adverse reaction would include deaths, hospitalizations or permanent alterations in health status. In theory, the HPV vaccine is causing 2.5 times more SAE’s than deaths from cervical cancer. Is the risk worth an unproven benefit? Since the vaccine does not eliminate the need for Pap smears due to the possibility that other strains might cause HPV infections, there is certainly no cost benefit to HPV vaccines.

Cervical cancer is preventable by Pap smears and Loop Electrosurgical Excision Procedure (LEEP), which have been proven to be safe and effective. But, how can HPV vaccines be justified without sufficient data?

Tomlijenovic and Shaw pointed out the safety assessment of the HPV vaccine clinical trials. Merck, a pharmaceutical company with the branded vaccine Gardasil, conducted clinical trials that used an aluminum-containing placebo and their product that also contains aluminum adjuvants. The trials showed that a large portion of the adverse reactions from the HPV vaccine were due to the effect of the aluminum adjuvants – a neurotoxin.

Contrary to claims that cervical cancer is the second most common cancer in women worldwide, existing data shows that this only applies to developing countries. With this in mind, HPV vaccines are the most expensive vaccines on the market, making it unlikely that those developing countries would ever benefit from them.

French Parliament Investigates HPV Vaccination Campaigns

A three hour debate in Paris concerning the safety, efficacy and necessity of HPV vaccines in French cervical cancer prevention programs was presented to the French Parliament, French Senate, health authorities, medical professionals and the public in May. This discussion was the first time a western government has called experts to testify about the adverse reactions to vaccines.

The debate was spurred by an open letter to the French Minister of Health calling for investigative action towards various aspects of HPV vaccination campaigns. The letter was signed by more than 200 medical professionals, confirming their agreement about safety concerns regarding the vaccines.

CMSRI funded researchers from around the world were in attendance at the debate to weigh in on this hot topic. They shed light on various issues to the discussion board about aluminum adjuvants and human papillomavirus, also known as HPV.

A member of the European Parliament opened the meeting with a speech that stated research findings and the actions necessary to protect the public health. Michele Rivasi opened with – Vaccines are unnecessary, dangerous to many and certainly a huge drain on public health funds.

Rivasi mentioned CMSRI advisory board members and funded researchers during her opening speech by highlighting the findings from Christopher Shaw, Lucija Tomljenovic, Stephanie Seneff, Yeduda Shoenfeld, Chris Exley, and Romain Gherardi – blaming the toxicity of aluminum salts used as adjuvants in vaccines cause adverse reactions.

The injection of aluminum salts could be the source of the unexplained “increase in the number of pathologies reported because they migrate through the body until they reach and accumulate in the brain.  In certain predisposed individuals, very serious adverse effects have been observed following vaccination: death, convulsions, fainting, autistic disorders, Guillain-Barre syndrome, transverse myelitis, facial paralysis, chronic fatigue syndrome, autoimmune diseases, pulmonary embolisms, macrophagic myofasciitis, pancreatitis and others.”

After Rivasi continued with other statements, she urged the need of extensive research before the parliament continues to vaccinate. Finishing with – research before consent, you can’t unvaccinate.

The discussion led to four round tables where CMSRI researchers presented their findings to the French Parliament and others, making the open forum history. The open conversation in Paris is paving the way for other countries to examine the risks vaccines pose on health.